A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators
نویسندگان
چکیده
منابع مشابه
High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice
OBJECTIVE Recently, several drugs have been shown to exert beneficial effects for metabolic syndrome through mild regulation of mitochondrial function. Hence, we explored a strategy of targeting mitochondrial function to improve glucose and lipid metabolism. RESEARCH DESIGN AND METHODS Mitochondrial membrane potential (Deltapsim) is a marker of mitochondrial function; therefore, we set up a h...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2010
ISSN: 1741-7007
DOI: 10.1186/1741-7007-8-100